Antimicrobial photodynamic therapy and its applicability in aquaculture systems and aquatic animal health management: An overview
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Abstract
Global aquaculture production in 2012 touched new high of 90.4 million tonnes including 66.6 million tonnes of food fish and 23.8 million tonnes of aquatic algae providing 19.2 kg per capita food fish suppy. Aquaculture is reported to suffer heavy production and financial losses due to fish infections caused by microbial pathogens. Therefore in order to make aquaculture industry more sustainable, effective strategies to control fish infections are urgently needed. Antimicrobial Photodynamic Therapy (aPDT) is an emerging, low-cost anti-microbial approach to the treatment of locally occurring infections and also for the treatment of aquaculture water and waste waters. Already proven effective in various medical and clinical applications, it utilizes three vital components: a photosensitizing agent (PS), a light source of an appropriate wave length and oxygen. aPDT has got a potential of being a preferred choice over antibiotics in aquaculture systems because of its non-target specificity, few side effects, lack of the pathogenicity reversal and re-growth of the micro-organism after treatment and the lack of development of resistance mechanisms. The technique has been proved effective in vitro against bacteria (including drug-resistant strains), yeasts, fungi, viruses, parasites and even the stubborn biofilms. Although preliminary results indicate that this technology has a high potential to disinfect waters in aquaculture system and also in hatcheries and seed production units, but it clearly needs more deep knowledge and multi-dimenstional approach.
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Keywords
Antibiotic resistance, Antimicrobial photodynamic therapy, Fish farming, Photosensitizer
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Antimicrobial photodynamic therapy and its applicability in aquaculture systems and aquatic animal health management: An overview. (2016). Journal of Applied and Natural Science, 8(1), 506-514. https://doi.org/10.31018/jans.v8i1.826
