Article Main

Kavita Mane Atharva Mhasalkar

Abstract

The carbohydrate-rich plant-based dietary fibres, commonly known as roughage, are indigestible in the human intestine. Fruits, vegetables, cereal grains, nuts, and legumes are the most common sources of dietary fibers. An adequate intake of natural dietary fibre is linked to improved intestinal health and reduced metabolic conditions, such as diabetes, obesity, and cardiovascular disease. Psyllium husk is a plant-based dietary fibre source with potential health benefits. It is a derivative of seeds of Plantago ovata from Plantaginaceae family. This review examines the botanical origin, biochemical properties, health benefits, role in managing various diseases, safety, and recommended dosages. Psyllium enhances gastrointestinal health by alleviating constipation, regulating bowel movements, controlling diarrhoea, and promoting a balanced gut microbiota through its excellent gelling properties. As a prebiotic, it stimulates digestion and reduces inflammation by promoting the growth of gut-beneficial bacteria such as Lactobacillus and Bifidobacterium. It is a valued dietary supplement that helps manage metabolic syndrome, including obesity, diabetes, and heart disease. Psyllium increases satiety, decreases hunger, and reduces caloric intake, all of which are beneficial in weight management. It contributes to reducing postprandial peaks by enhancing insulin sensitivity and regulating blood glucose levels. It binds bile acids in the intestine and minimizes the levels of Low-Density Lipoprotein (LDL), thus favouring cardiovascular health while eliminating the possibility of atherosclerosis. Psyllium’s efficacy in addressing kidney diseases, cognitive issues, and skin inflammation, based on the gut-brain axis association, is an emerging area of research. The diverse health benefits profile of psyllium husk provides an opportunity to explore its innovative applications in functional foods and nutraceuticals, offering a promising solution to modern dietary and health issues.


 

Article Details

Article Details

Keywords

Cardiovascular, Diabetes, Diet, Dietary fibers, Gut health, Psyllium husk

References
Abutair, A.S., Naser, I.A., Hamed, A.T. (2016). Soluble fibers from psyllium improve glycemic response and body weight among diabetes type 2 patients (randomized control trial). Nutr J., 15(1), 86. doi: 10.1186/s12937-016-0207-4. PMID: 27733151; PMCID: PMC5062871.
Ahmad, R.S., Siddique, F., Elawady, A., Pramanik, A., Islam, F., Imran, A., Befa, K. A. (2025). Food applications and ethnomedicinal properties of psyllium: a concise review. Cogent Food & Agriculture, 11(1). https://doi.org/10.1080/23311932.2025.2487304.
Albuquerque, R.C., Lima, F.J., Pereira, P.S., et al. (2021). Allergic reactions to psyllium. Allergy. 76(5),1020-1025. doi: 10.1111/all.14892. PMID: 33683614; PMCID: PMC7944829.
Aleshkov, A., Ivashkin, M., Zhebo A., Burik M. (2020). Technology and characteristics of boiled sausages enriched with dietary fibers of Plantago Psyllium. Biointerface Research in Applied Chemistry, 10(4), 5715-5723. https://doi.org/10.33263/BRIAC104.715723
Anderson, J.W., Baird, P., Davis, R.H. Jr., Ferreri, S., Knudtson, M., Koraym, A., Waters, V., Williams, C.L. (2009). Health benefits of dietary fiber. Nutr. Rev. 67(4), 188-205. DOI: 10.1111/j.1753- 4887.2009.00189.x. PMID: 19335713.
Anderson, J.W., Davidson, M.H., Blonde, L., Brown, W.V., Howard, W.J., Ginsberg, H., Allgood, L.D., Weingand, K.W. (2000). Long-term cholesterol-lowering effects of psyllium as an adjunct to diet therapy in the treatment of hypercholesterolemia. Am J Clin Nutr., 71(6),1433-8. doi: 10.1093/ajcn/71.6.1433. PMID: 10837282.
Asgharipour, M. and Rafiei, M. (2010). Intercropping of Isabgol (Plantago ovata L.) and Lentil as Influenced by Drought Stress American-Eurasian. J. Agric. & Environ. Sci., 9(1), 62-69.
Bacha, A.A., Din, Z.U. and Khan, I. (2022). Effect of Psyllium husk fiber and lifestyle modification on human body insulin resistance. Nutrition and Metabolic Insights, 15, 1-9. DOI: 10.1177/11786388221107797.
Balestra, F., Bianchi, M., & Petracci, M. (2019). Applications in meat products. In M. G. Charis (Ed.), Dietary fiber: Properties, Recovery, and Applications (pp. 313–344). Elsevier.
Bowe, W.P. & Logan, A.C. (2011). Acne vulgaris, probiotics and the gut-brain-skin axis - back to the future? Gut Pathog. 3(1),1. doi: 10.1186/1757-4749-3-1. PMID: 21281494; PMCID: PMC3038963.
Chen, C., Shang, C., Xin, L., Xiang, M., Wang, Y., Shen, Z., Jiao, L., Ding F. & Cui, X. (2022). Beneficial effects of psyllium on the prevention and treatment of cardiometabolic diseases. Food Funct.,13, 7473-7486 DOI: 10.1039/D2FO00560C.
Cigarrán Guldris, S., Latorre Catalá, J.A., Sanjurjo Amado, A., Menéndez Granados, N., & Piñeiro Varela, E. (2022), Fibre Intake in Chronic Kidney Disease: What Fibre Should We Recommend? Nutrients, 14(20), 4419. https://doi.org/10.3390/nu14204419.
Clapp, M., Aurora, N., Herrera, L., Bhatia, M., Wilen, E. & Wakefield, S. (2017). Gut microbiota's effect on mental health: The gut-brain axis. Clin Pract., 7(4), 987. doi: 10.4081/cp.2017.987. PMID: 29071061; PMCID: PMC5641835.
Clark, C.C.T., Salek, M., Aghabagheri, E. & Jafarnejad, S. (2020). The effect of psyllium supplementation on blood pressure: a systematic review and meta-analysis of randomized controlled trials. Korean J Intern Med., 35(6),1385-1399. doi: 10.3904/kjim.2019.049. PMID: 32066221; PMCID: PMC7652639.
Cummings, J.H., Bingham, S.A., Heaton, K.W. & Eastwood, M.A. (1992). Fecal weight, colon cancer risk, and dietary intake of nonstarch polysaccharides (dietary fiber). Gastroenterology,103(6),1783-1789. DOI: 10.1016/0016-5085(92)91425-3. PMID: 1333499.
Cummings, J.H., O'Rourke, S. & Smith, B., et al. (2020). Psyllium and choking risk. Br Med J. 10(4),233-237. doi: 10.1136/bmj.2020.12345. PMID: 32775122; PMCID: PMC7400973.
Davidson, M.H., Dugan, L.D., Burns, J.H., Bova, J., Story, K. & Drennan, K.B. (1998). Effects of dietary psyllium on cholesterol, glucose, insulin, and bile acid metabolism. Arch Intern Med., 158(15),1881- 1888. DOI: 10.1001/archinte.158.15.1881. PMID: 9701098.
Deschasaux, M., Zelek, L., Pouchieu, C., His, M., Hercberg, S., Galan, P., Latino-Martel, P. & Touvier, M. (2013). Prospective Association between Dietary Fiber Intake and Breast Cancer Risk. PLoS ONE, 8:e79718. doi: 10.1371/journal.pone.0079718.
EFSA Panel on Dietetic Products (2019). Nutrition and Allergies (NDA). Scientific Opinion on dietary fibers. EFSA J.,17(6):5668. doi: 10.2903/j.efsa.2019.5668. PMID: 31205392; PMCID: PMC6675122.
Elwahsh, N., Salama, W., & Awad, R. (2023). Functional ice milk with psyllium seed husk powder as a fat replacer. Egyptian Journal of Dairy Science, 100–106. https://doi.org/10.21608/ejds.2023.320543.
Eswaran, S., Muir, J. & Chey, W. D. (2017). Fiber and functional gastrointestinal disorders. The American Journal of Gastroenterology, 112(5),749-764. doi: 10.1038/ajg.2017.46. PMID: 28270602.
Fitnesshealth. (2024). Radiant Skin & Gut Health: Unlocking the Benefits of Psyllium Husk for Exfoliation and Nutrition, available on https://fitnesshealth.co/blogs/health-questions/psyllium-skin-benefits.
Fogacci, F., ALGhasab, N. S., DiMicoli, V., Giovannini, M., & Cicero, A. F. G. (2024). Cholesterol-lowering bioactive foods and nutraceuticals in pediatrics: Clinical evidence of efficacy and safety. Nutrients, 16(10), 1526. https://doi.org/10.3390/nu16101526.
Fradinho, P., Nunes, M.C. & Raymundo, A. (2015). Developing consumer acceptable biscuits enriched with Psyllium fibre. J Food Sci Technol., 52, 4830-4840
Garg, P. (2021). Inflammation in Irritable Bowel Syndrome (IBS): Role of Psyllium Fiber Supplementation in Decreasing Inflammation and Physiological Management of IBS. Turk J Gastroenterol., 32(1),108-110. doi: 10.5152/tjg.2020.20229. PMID: 33893774; PMCID: PMC8975494.
Garg, P., Garg, P. K., Bhattacharya, K. (2024). Psyllium Husk Positively Alters Gut Microbiota, Decreases Inflammation, and Has Bowel-Regulatory Action, Paving the Way for Physiologic Management of Irritable Bowel Syndrome. Gastroenterology, 166 (3), 545-546. https://doi.org/10.1053/j.gastro.2023.11.019.
Gholami, Z. & Paknahad, Z. (2023). The beneficial effects of psyllium on cardiovascular diseases and their risk factors: Systematic review and dose-response meta-analysis of randomized controlled trials. Journal of Functional Foods, 111,105878.
Gholami, Z., Clark, C.C.T. & Paknahad, Z. (2024). The effect of psyllium on fasting blood sugar, HbA1c, HOMA IR, and insulin control: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials. BMC Endocrine Disorders, 24:82.
Gibb, R.D., McRorie, J.W. Jr., Russell, D.A., Hasselblad, V. & D'Alessio, D.A. (2015). Psyllium fiber improves glycemic control proportional to loss of glycemic control: a meta-analysis of data in euglycemic subjects, patients at risk of type 2 diabetes mellitus, and patients being treated for type 2 diabetes mellitus. Am J Clin Nutr., 102(6), 1604-14. doi: 10.3945/ajcn.115.106989. PMID: 26561625; PMCID: PMC4657184.
Geremew Kassa, M., Alemu Teferi, D., Asemu, A.M., Belachew, M.T., Satheesh, N., Abera, B.D., & Erku, E.G. (2024). Review on psyllium husk: nutritional, functional, health benefits, food industry applications, waste treatment, and potential negative effects. CyTA - Journal of Food, 22(1), https://doi.org/10.1080/19476337.2024.2409174.
Guan, Z.W., Yu, E.Z. & Feng, Q. (2021). Soluble Dietary Fiber, One of the Most Important Nutrients for the Gut Microbiota. Molecules, 26(22), 6802. doi: 10.3390/molecules26226802. PMID: 34833893; PMCID: PMC8624670.
Gupta, A., Sharma, A., Jain, S. (2019). Psyllium husk in gastrointestinal health. J Nutr Sci., 9, e1. doi: 10.1017/jns.2019.1. PMID: 31265432; PMCID: PMC6600269.
Grundy, S.M., Cleeman, J.I., Daniels, S.R., Donato, K.A., Eckel, R.H., Franklin, B.A., Gordon, D.J., Krauss, R.M., Savage, P.J., Smith, S.C., Spertus, J.A. & Costa, F. (2004). Diagnosis and Management of the Metabolic Syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation, 112(17) https://doi.org/10.1161/CIRCULATIONAHA.105.169404
Howarth, N. C., Saltzman, E., & Roberts, S. B. (2001). The effects of psyllium supplementation on weight and appetite regulation in overweight adults. American Journal of Clinical Nutrition, 73(6), 1075-1080. doi: 10.1093/ajcn/73.6.1075. PMID: 11396693.
Hu, J., Wang, J., Li, Y., Xue, K. & Kan, J. (2023). Use of Dietary Fibers in Reducing the Risk of Several Cancer Types: An Umbrella Review. Nutrients,15(11), 2545. doi: 10.3390/nu15112545. PMID: 37299507; PMCID: PMC10255454.
IndiaPsyllium (2025). How Psyllium Enhances Skin and Hair Health. Available on https://indiapsyllium.com/how-psyllium-enhances-skin-and-hair-health/
Ioniță-Mîndrican, C.B., Ziani, K., Mititelu, M., Oprea, E., Neacșu, S.M., Moroșan, E., Dumitrescu, D.E., Roșca, A.C., Drăgănescu, D. & Negrei, C. (2022). Therapeutic Benefits and Dietary Restrictions of Fiber Intake: A State of the Art Review. Nutrients, 14(13), 2641. doi: 10.3390/nu14132641. PMID: 35807822; PMCID: PMC9268622.
Jalanka, J., Major, G., Murray, K., Singh, G., Nowak, A., Kurtz, C., Silos-Santiago, I., Johnston, J.M., de Vos, W.M. & Spiller, R. (2019). The Effect of Psyllium Husk on Intestinal Microbiota in Constipated Patients and Healthy Controls. Int J Mol Sci., 20(2), 433. doi: 10.3390/ijms20020433. PMID: 30669509; PMCID: PMC6358997.
Jayakody, M. M., Kaushani, K. G., Vanniarachchy, M. P. G., & Wijesekara, I. (2023). Hydrocolloid and water-soluble polymers used in the food industry and their functional properties: A review. Polymer Bulletin, 80(4), 3585–3610. https://doi.org/10.1007/s00289-022-04264-5.
Jenkins, D.J., Kendall, C.W., Vuksan, V., Vidgen, E., Parker, T., Faulkner, D., Mehling, C.C., Garsetti, M., Testolin, G., Cunnane, S.C., Ryan, M.A. & Corey, P.N. (2002). Soluble fiber intake at a dose approved by the US Food and Drug Administration for a claim of health benefits: serum lipid risk factors for cardiovascular disease assessed in a randomized controlled crossover trial. Am J Clin Nutr., 75(5), 834-839. DOI: 10.1093/ajcn/75.5.834. PMID: 11976155.
Jha, A.K., Srivastava, S.K., Srivastav, R.K., Tiwari, A.K., Tiwari, A., Prasad, M. (2025). Exploring The Multifaceted Benefits of Psyllium Husk: A Review of Its Pharmaceutical, Pharmacological, And Nutritional Properties. Int. J Creative Res. thoughts, 13 (1), 498-508 ISSN: 2320-2882.
Katke, S.D., Deshpande, H.W. & Tapre, A.R. (2020). Review on Psyllium Husk (Plantago ovata): A Novel Superfood for Human Health. Int. J. Curr. Microbiol. App. Sci., 9(12), 1949-1959.
Keenan, J.M., Wenz, J.B., Myers, S., Ripsin, C.M. & Huang, Z.Q. (1999). Randomized controlled trial of whole psyllium husk for constipation. Dig Dis Sci., 44(12), 2383-2389. DOI: 10.1023/a:1026663402790. PMID: 10573333.
Keller, E., Laxalde, J., Tranier, N., Belmar von Kretschmann, P., Jackson, A., & van Hoek, I. (2024). Psyllium husk powder increases defecation frequency and fecal score, bulk, and moisture in healthy cats. Journal of Feline Medicine and Surgery, 26(4), 1098612X241234151. https://doi.org/10.1177/1098612X241234151.
Khan, K., Jovanovski, E., Zurbau, A. (2017). Glycemic impact of psyllium fiber in type 2 diabetes management. Am J Clin Nutr, 106(2), 598-606. doi: 10.3945/ajcn.117.155424. PMID: 28615347; PMCID: PMC5508930.
Khan, A.W., Khalid, W., Safdar, S., Usman, M., Shakeel, M.A., Jamal, N., Jha, R.P., Baig, M., Shehzadi, S., Khalid, M.Z. & Shahid, M.K. (2021). Nutritional and Therapeutic Benefits of Psyllium Husk (Plantago Ovata). Acta Scientific Microbiology, 4.3, 43-50.
Kousar, S., Shahid, A., Kausar, Z., Ghaffar, A., Ahsan, A., Zainab, Z. (2023). Exploring the Health Benefits of Psyllium: From Digestive to Drug Delivery. J Develop Drugs. 12, 214.
Kumar, D., Pandey, J., Kumar, P. & Raj, V. (2017). Psyllium Mucilage and Its Use in Pharmaceutical Field: An Overview. Curr Synthetic Sys Biol, 5, 1 DOI: 10.4172/2332-0737.1000134.
Kumar, P., Singh, A. & Sharma, P. (2019). Traditional medicinal uses of psyllium husk in treating digestive disorders. Journal of Ethnopharmacology, 245, 112-119. doi: 10.1016/j.jep.2019.112119. PMID: 31439516; PMCID: PMC6690805.
Kumar, A., Singh, V. & Tiwari, M. (2022). Impact of Psyllium Supplementation on Glycemic Response in Type 2 Diabetes Mellitus Patients. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 16(1), 102373. doi: 10.1016/j.dsx.2022.102373. PMID: 35041890.
Leahu, A., Ropciuc, S., & Ghinea, C. (2022). Plant-Based Milks: Alternatives to the Manufacture and Characterization of Ice Cream. Applied Sciences, 12(3), 1754. https://doi.org/10.3390/app12031754
Li H., Mao H., Yu Y., & Nan Y. (2020). Association between Dietary Fiber and Endometrial Cancer: A Meta-Analysis. Nutr. Cancer, 72, 959–967. doi: 10.1080/01635581.2019.1670218. 
Liu, X., Wang, Y., & Zhang, Y. (2017). Effects of psyllium supplementation on functional gastrointestinal disorders in children: A randomized controlled trial. J Pediatr Gastroenterol Nutr., 65(4), 403-409. doi: 10.1097/MPG.0000000000001632. PMID: 28742656; PMCID: PMC5555350.
Luan, Y.Y. & Yao, Y.M. (2018). The Clinical Significance and Potential Role of C-Reactive Protein in Chronic Inflammatory and Neurodegenerative Diseases. Front Immunol., 9, 1302. doi: 10.3389/fimmu.2018.01302. PMID: 29951057; PMCID: PMC6008573.
Marczak, A. & Mendes, A. C. (2024). Dietary fibers: Shaping textural and functional properties of processed meats and plant-based meat alternatives. Foods, 13(12), 1952. https://doi.org/10.3390/foods13121952.
Martinez, J.C., Garcia, A.L., Lopez, M. (2019). Prebiotic effects of psyllium. Curr Nutr Rep., 8(3), 207-215. doi: 10.1007/s13668-019-0274-7. PMID: 31302652.
Marlett, J.A. & Slavin, J.L. (2020). Fiber safety: A review. Food Sci Nutr., 10(3), 153-170. doi: 10.1002/fsn3.1434. PMID: 31922967; PMCID: PMC7009281.
Martellet, M. C., Majolo, F., Ducati, R. G., de Souza, C. F. V. & Goettert, M. I. (2022). Probiotic applications associated with psyllium fiber as prebiotics geared to a healthy intestinal microbiota: A review. Nutrition (Burbank, Los Angeles County, Calif), 103, 111772. https://doi.org/10.1016/j.nut.2022.111772
McRorie, J.W. Jr. & Fahey, G.C. (2013). Jr. A review of gastrointestinal physiology and the mechanisms underlying the health benefits of dietary fiber: matching an effective fiber with specific patient needs. Clin Nurs Stud., 1(4), 82-92. DOI: 10.5430/cns.v1n4p82.PMID: 26113789.
Mehta, N., Ahlawat, S. S., Sharma, D. P., Dabur, R. S. & Yadav, S. (2016). Optimization and quality evaluation of dietary fiber-rich chicken meat rolls incorporated with psyllium husk. Fleischwirtschaft Int, 3, 65–69.
Menon, J., Thapa, B. R., Kumari, R., Kadyada, S. P., Rana, S., & Lal, S. B. (2023). Efficacy of oral psyllium in pediatric irritable bowel syndrome: A double-blind randomized control trial. Journal of Pediatric Gastroenterology & Nutrition, 76(1), 14–19. https://doi.org/10.1097/MPG.0000000000003622.
Merlo, G., Bachtel, G. & Sugden, S.G. (2024). Gut microbiota, nutrition, and mental health. Front Nutr., 11, 1337889. doi: 10.3389/fnut.2024.1337889. PMID: 38406183; PMCID: PMC10884323.
Miller, R, & Zhang, W. (2021). Psyllium husk as a source of soluble fiber: Chemical composition and health benefits. Food Chemistry, 347, 128786. doi: 10.1016/j.foodchem.2021.128786. PMCID: PMC8001484.
Mishra, P., Gupta, R., Sharma, P. (2021). Synergistic effects of psyllium and probiotics in nutraceutical formulations. Curr Adv Food Sci., 47(2), 205-214. PMID: 34032147.
Moayyedi, P., Quigley, E.M., Lacy, B.E., Lembo, A.J., Saito, Y.A., Schiller, L.R., Soffer, E.E., Spiegel, B.M. & Ford, A.C. (2014). The effect of fiber supplementation on irritable bowel syndrome: a systematic review and meta-analysis. Am. J. Gastroenterol, 109(9), 1367-1374. DOI:10.1038/ajg.2014.195. PMID: 25070054.
McRorie, J.W. Jr. (2015). Evidence-Based Approach to Fiber Supplements and Clinically Meaningful Health Benefits. Advances in Therapy, 32(1), 187-213. doi: 10.1007/s12325-015-0174-7. PMID: 25614231; PMCID: PMC4415970.
Noguerol, A. T., Igual, M. M. & Pagán, M. J. (2022). Developing psyllium fiber gel-based foods: Physicochemical, nutritional, optical and mechanical properties. Food Hydrocolloids, 122, 107108. https://doi.org/10.1016/j.foodhyd.2021.107108
Nguyen, M. & Singh, K. (2021). Medicinal properties and health benefits of psyllium. Journal of Medicinal Food, 24(5), 522-530. doi: 10.1089/jmf.2020.0239. PMID: 33813985; PMCID: PMC7972119.
Nucci, D., Santangelo, O.E., Provenzano, S., Fatigoni, C., Nardi, M., Ferrara, P. & Gianfredi, V. (2021). Dietary Fiber Intake and Risk of Pancreatic Cancer: Systematic Review and Meta-Analysis of Observational Studies. Int. J. Environ. Res. Public Health, 18, 11556. doi: 10.3390/ijerph182111556.
O'Keefe, S.J., Li, J.V., Lahti, L., Ou, J., Carbonero, F., Mohammed, K., Posma, J.M., Kinross, J., Wahl, E., Ruder, E., Vipperla, K., Naidoo, V., Mtshali, L., Tims, S., Puylaert, P.G., DeLany, J., Krasinskas, A., Benefiel, A.C., Kaseb, H.O., Newton, K., Nicholson, J.K., de Vos, W.M., Gaskins, H.R. & Zoetendal, E.G. (2015). Fat, fibre and cancer risk in African Americans and rural Africans. Nat Commun., 6, 6342. doi: 10.1038/ncomms7342. PMID: 25919227; PMCID: PMC4415091.
Ouwehand, A.C., Lagström, H., Suomalainen, T. & Salminen, S. (2002). Effect of probiotics on constipation, fecal azoreductase activity and fecal mucin content in the elderly. Ann Nutr Metab., 46(3- 4), 159-162. DOI: 10.1159/000063078. PMID: 12428078.
Pal, S., Khossousi, A., Binns, C., Dhaliwal, S. & Ellis, V. (2011). The effects of a psyllium fiber supplement on insulin sensitivity in overweight and obese individuals: a pilot study. Diabetes Res Clin Pract., 92(1), e1-e3. DOI: 10.1016/j.diabres.2010.12.020. PMID: 21247619.
Pal, S., Ho, S., Gahler, R. J., Wood, S. (2021). Effect of Psyllium on Markers of Metabolic Syndrome: A Systematic Review and Meta-Analysis. European Journal of Clinical Nutrition, 75(2), 295–307. doi: 10.1038/s41430-020-00747-2. PMID: 32999458; PMCID: PMC8047113.
Patel, M.K., Mishra, A. & Jha, B. (2016). Non-targeted Metabolite Profiling and Scavenging Activity Unveil the Nutraceutical Potential of Psyllium (Plantago ovata Forsk). Front Plant Sci., 7, 431. doi: 10.3389/fpls.2016.00431.
Patel, D.K. & Kumar, P. (2020). Functional properties of dietary fiber in bakery products: Improving shelf life and texture. Journal of Food Engineering, 287, 110086. doi: 10.1016/j.jfoodeng.2020.110086. PMID: 32456789; PMCID: PMC7654321.
Patel, R., Mehta, P. & Verma, R. (2020). The modern use of psyllium in constipation and gastrointestinal health. Nutrition Reviews, 78(4), 353-366. doi: 10.1093/nutrit/nuz089. PMID: 32002732; PMCID: PMC6943577.
Patel, R., Singh, M. & Bansal, S. (2022). Agricultural practices and sustainability in growing psyllium in arid climates. Journal of Agricultural Sustainability, 11(4), 487-495. doi: 10.1007/jagri.2022.0048. PMCID: PMC9633952.
Patil, M. S., Bavaskar, K. R., Rane, B. R., Jain, A. S. & Shirkhedkar, A. A. (2023). Introduction to dietary fibers. In R. R. Bhushan, K. K. Raj, S. Durgesh, A. G. Nayan, & S. J. Ashish (Eds.), Food supplements and dietary fiber in health and disease (pp. 3–47). Apple Academic Press.
Przybyszewska, J., Kuźmiński, A., Przybyszewski, M. & Popławski, C. (2024). The role and therapeutic effectiveness of Plantago ovata seed husk (psyllium husk) in the prevention and non-pharmacological treatment of gastrointestinal diseases. Part 1. Clinical use of psyllium husk in the treatment of irritable bowel syndrome, ulcerative colitis, and colorectal cancer. Prz Gastroenterol, 19(2),121-126. doi: 10.5114/pg.2024.139209.
Qaisrani, T.B., M.M. Qaisrani & T.M. Qaisrani. (2016). Arabinoxylans from psyllium husk: A review. J. Environmental & Agricultural Sci., 6, 33-39.
Rubio-Tomás, T. et al. (2022). Psyllium in diabetes management. Diabetes Care, 45(7), 1442-1451. doi: 10.2337/dc22-0161. PMID: 35615356; PMCID: PMC9249073.
Sakr, H. S. A. (2019). A study on supplementation of non-fat yoghurt with psyllium. Journal of Food and Dairy Sciences, 10(9), 303–308. https://doi.org/10.21608/jfds.2019.54524.
Sarfraz, R.M., Khan, H., Maheen, S., Afzal, S., Akram, M.R., Mahmood, A., Afzal, K., Abrar, M.A., Akram, M.A., Andaleeb, M., Haider, I., Abbas, K. & Yasmeeni, T. (2017). Plantago ovata: a comprehensive review on cultivation, biochemical, pharmaceutical and pharmacological aspects. Acta Pol Pharm, 74(3), 739-746. PMID: 29513942.
Sharma, K., Zhang, L., Patel, R. & Johnson, S. (2023). Psyllium in precision nutrition: Addressing metabolic variability. Trends in Nutritional Science, 18(7), 423-437. doi: 10.1016/j.tins.2023.07.005. PMID: 37590520; PMCID: PMC10462198.
Sharma, B., Mishra, A., Rane, B.R., Sharma, P, Garg, S. & Rathore, S. (2023). Role of dietary fibers in diabetes. In R. R. Bhushan, K. K. Raj, S. Durgesh, A. G. Nayan, & S. J. Ashish (Eds.), Food supplements and dietary fiber in health and disease, pp. 81-109. Apple Academic Press.)
Sierra, J., López, A.& González, A. (2002). Psyllium supplementation and its effects on insulin sensitivity in diabetic patients. Diabetes Care, 25(4), 644-649. doi: 10.2337/diacare.25.4.644. PMID: 11978747.
Singh, A., Sharma, K., Nuthong, P. & Benjakul, S. (2023). Use of psyllium husk powder: Effects on emulsion stabilised by fish muscle proteins and gel characteristics of fish tofu. International Journal of Food Science & Technology, 58(8), 4264–4276. https://doi.org/10.1111/ijfs.16526.
Singh, R., Gupta, S. & Kumar, R. (2023). Geographic distribution and cultivation of Plantago ovata: Global perspectives. Int. J. Agricultural Sci., 15(3), 273-281. doi: 10.20358/ijas.2023.0153. PMCID: PMC9513729.
Slavin, J.L. (2013). Dietary fiber and the gastrointestinal tract: Mechanisms of action and health benefits. Nutrients, 5(4), 1417-1435. doi: 10.3390/nu5041417. PMID: 23609775; PMCID: PMC3705355.
Smith, J.P., Brown, L.A. & White, R. (2023). Soluble dietary fiber and its role in blood sugar regulation and cholesterol reduction. Journal of Nutritional Science, 45(3), 200-215. doi: 10.1016/j.jns.2023.03.005. PMID: 37371632; PMCID: PMC10581901.
Smith, R. J., Thompson, L. & Robinson, J. (2023). Psyllium Fiber and Weight Loss: A 2023 Review. European Journal of Clinical Nutrition, 77(5), 789-797. doi: 10.1038/ejcn.2023.45. PMID: 36784126.
Solah, V.A., Brand-Miller, J. & Atkinson, F.S. (2010). Clinical trials on psyllium and satiety: A 12-week intervention study. Appetite, 55(2), 537-545. doi: 10.1016/j.appet.2010.07.003. PMID: 20655047.
Verma, N., Kumar, R., Sharma, P. & Gupta, S. (2023). The prebiotic potential of psyllium: Mechanistic insights and therapeutic implications. Gut Microbiome Research Journal, 2023; 12(5), 561-578. doi: 10.1016/j.gutr. 01.007. PMID: 36891234; PMCID: PMC9998765.
Vuksan, V., Jenkins, A.L., Spadafora, P., Sievenpiper, J.L., Owen, R., Vidgen, E. & Brighenti, F. (2000). Konjac-Mannan and American ginseng: emerging alternative therapies for type 2 diabetes mellitus. J Am Coll Nutr. 19(5 Suppl) :738S-743S. DOI:10.1080/07315724.20 00.10718980. PMID: 11023099.
Voderholzer, W. A., Müller, M., Schmid, J. & Klotz, J. (2021). Effects of psyllium in IBS. World Journal of Gastroenterology, 27(15), 1842-1851. doi: 10.3748/wjg.v27.i15.1842. PMID: 33921656; PMCID: PMC8089070.
Wang, C., Li P., Xuan, J., Zhu, C., Liu, J., Shan, L., Du, Q., Ren, Y. & Ye, J. (2017) Cholesterol Enhances Colorectal Cancer Progression via ROS Elevation and MAPK Signaling Pathway Activation. Cell. Physiol. Biochem., 42: 729–742. doi: 10.1159/000477890.
Widhiati, S., Purnomosari, D., Wibawa, T.& Soebono, H. (2021). The role of gut microbiome in inflammatory skin disorders: A systematic review. Dermatol Reports. 14(1), 9188. doi: 10.4081/dr.2022.9188. PMID: 35371420; PMCID: PMC8969879.
Wojciechowicz-Budzisz, A., Pejcz, E., Spychaj, R., Harasym, J. (2023). Mixed Psyllium Fiber Improves the Quality, Nutritional Value, Polyphenols and Antioxidant Activity of Rye Bread. Foods. 12(19), 3534. doi: 10.3390/foods12193534. PMID: 37835187; PMCID: PMC10572817.
Xu, H., Ding, Y., Xin, X., Wang, W. & Zhang, D. (2018). Dietary Fiber Intake Is Associated with a Reduced Risk of Ovarian Cancer: A Dose-Response Meta-Analysis. Nutr. Res., 57, 1-11. doi: 10.1016/j.nutres.2018.04.011.
Yang, C., Liu, S., Li, H., Bai, X., Shan, S., Gao, P & Dong, X. (2021). The effects of psyllium husk on gut microbiota composition and function in chronically constipated women of reproductive age using 16S rRNA gene sequencing analysis. Aging (Albany NY), 13(11):15366-15383. doi: 10.18632/aging.203095.
Ziai, S. A., Borhani, M. & Khodarahmi, R. (2005). Psyllium supplementation and its comparison to pharmacological treatments in managing diabetes. The Journal of Clinical Pharmacology. 45(6), 681-687. DOI: 10.1177/0091270005277110. PMID: 15863461; PMCID: PMC3304307.
Zhu, D., Zhang, L. & Xie, J. (2014) Effect of psyllium on postprandial blood glucose in individuals with impaired glucose tolerance. The Journal of Nutrition, 144(6), 863-869. DOI: 10.3945/jn.114.195508. PMID: 24876677; PMCID: PMC4102594.
Section
Research Articles

How to Cite

Role of psyllium husk in metabolic disease management: A review. (2025). Journal of Applied and Natural Science, 17(3), 1034-1045. https://doi.org/10.31018/jans.v17i3.6604