D. B. Zala Vikram Khan V. K. Das


A study on biochemical parameters in clinically suspected and laboratory- confirmed leptospirosis cases was conducted in the Union Territory of Dadra and Nagar Haveli. Out of 50 clinically suspected samples of leptospirosis, 38% were positive from both ELISA IgM and rapid card test. In the present study, liver markers such as bilirubin, Serum Glutamate Oxalo acetic Transaminase (SGOT) and Serum Glutamate Pyruvic Transaminase (SGPT) encountered elevation 68%, 100% and 89% respectively in leptospiosis positive patent while 89% and 48 %
of positive patients showed elevation in kidney marker, creatinine and blood urea. On the basis of liver and renal functions, a hospital can develop its own clinical algorithm to suspect the case of leptospirosis.


Download data is not yet available.


Metrics Loading ...




Biochemical parameters, Immunochromatogaphy, SGOT, SGPT, Leptospirosis

Charoonruangrit, S. and Boonpucknavig, S. (1964). Leptospirosis at Chulalongkorn Hospital: A report of 54 cases. J. of Medical Association. Thailand, 47: 653-659.
Desai, S., van Treeck, U., Lierz, M., Espelage, W., Zota, L. and Sarbu, A. (2009). Resurgence of field fever in a temperate country: an epidemic of leptospirosis among seasonal strawberry harvesters in Germany in 2007. Clinical Infectious Disease, 48: 691-697.
Levett, P. N. (2001). Leptospirosis. Clinical Microbioliology Reviews, 14: 296-326.
Patel, B. K., Gandhi, S. J. and Desai, D. C. (2006). Clinicoepidemiological aspect of leptospirosis in South Gujarat. Indian J. of medical Microbiology, 24(4):322-325.
Mamuthausethupathi, Shivakumar, S., Suguna, R., Jaykumar, M. R., Vijayakumar R, Cor, E. and Carrington, D. G. (1995). Leptospiorosis in Madras – A clinical & seriological study (1990 – 91) Journal of the Association of Physician India, 43(7):456-458.
Meenakshi, M., Anuradha, De. and Dilip, T. (2009). Leptospirosis outbreak in 2005: L.T.M.G. hospital experience. Indian Journal of Medical Microbiology, 27 (2):153-155.
Prabhu, N., Joseph, P.I.D. and Chinnaswamy, P. (2010). Seroepidemiological trends of human leptospirosis in Coimbatore, India between 2007 and 2009. Advances in Applied Science Research, 1: 113-119.
Sethi, S., Sharma, N., Kakkar, N., Taneja, J., Chatterjee, S.S. and Banga, S.S. (2010). Increasing trends of leptospirosis in northern India: a clinicoepidemiological study. PLOS Neglected Tropical Diseases, 4: 579.
Sugunan, A. P., Vijayachari, P., Sharma, S., Roy, S., Manickam, P., Natarajaseenivasan, K., Gupte, M. D. and Sehgal, S. C. (2009). Risk factors associated with leptospirosis during an outbreak in Middle Andaman, India. Indian Journal of Medical Research, 130(1): 67-73.
Velineni, S., Asuthkar, S., Umabala, P., Lakshmi, V. and Sritharan, M. (2007). Serological evaluation of leptospirosis in Hyderabad, Andhra Pradesh: A retrospective hospital-based study. Indian Journal of Medical Microbiology, 25: 24-7.
WHO (1999). Leptospirosis worldwide, World Health Organization; Wkly. Epidemiol. Rec., 74:237-242.
Citation Format
How to Cite
Zala, D. B., Khan, V., & Das, V. K. (2014). A study on few biochemical parameters of clinically suspected and laboratory confirmed Leptospirosis cases. Journal of Applied and Natural Science, 6(1), 12–13. https://doi.org/10.31018/jans.v6i1.367
More Citation Formats:
Research Articles