Article Main

S. Ranjith Kumar K. Chozhan K. A. Murugesh R. Rajeswari K. Kumaran

Abstract

Psoralea corylifolia is the most important medicinal plant which has various secondary metabolites and its leaves are broadly used in many sectors due to its antimicrobial activity. This study aimed to find the bio-active compounds of chloroform extract of P. corylifolia leaves using Perkin-Elmer Gas Chromatography – Mass Spectrometry (GC-MS). The results of GC-MS compounds in the chloroform extract was appropriate to the database of National Institute of Standards and Technology (NIST). GC-MS analysis of chloroform extract of P. corylifolia leaves reveal the presence of bioactive compounds as Hexadecanoic acid, 3-hydroxy-, methyl ester , Hydroxylamine, O-decyl- , 2,4-Di-tert-butylphenol ) Cubenol , Neophytadiene , Phytol , Linoleic acid ethyl esterand 9,12,15-Octadecatrienoic acid, ethyl ester, (Z,Z,Z)- ) . These bio-active compounds are mainly responsible for various biological activities. Hence, this study will make a good way for the production of various products for curing various disease-causing pathogens by using P. corylifolia leaves.

Article Details

Article Details

Keywords

Psoralea corylifolia, GC-MS, antimicrobial, bio-active compounds

References
Dr. Duke's Phytochemical and Ethnobotanical Databases (1992- 2016). U. S. Department of Agriculture, Agricultural Research Service. Retrieved from: http://phytoche m.nal.usda.gov.
International Union for Conservation of Nature and Natural Resources (2013). Guidelines on the conservation of medicinal plants. International Union for Conservation of Nature and Natural Resources (IUCN), Gland Switzerland:
Kumar, S.M. & Manimegalai, S. (2008). Evaluation of larvicidal effect of Lantana camara L. against mosquito species Aedes aegypti and Culex quinquefasciatus. Adv. Biol. Res.,2, 39-43.
Manimegalai, S., Rajeswari, T., Shanmugam, R. & Rajalakshmi, G. (2010). Botanicals against Nuclear Polyhedrosis Virus infecting three breeds of mulberry silkworm, Bombyx mori L. Journal of Biopesticides, 3(1), 242 – 245.
Rastogi R.P.& Mehrotra, B.N.(1979). Compendium of Indian medicinal plants. (Vol 2), New Delhi, India: Central Drug Research, Lucknow and NISCAIR, 1979, 521.
Rukshana, M.S., Doss, A. & Kumari PusphaRani,T.P.(2017). Phytochemical screening and GC-MS analysis of leaf extract ofPergulariadaemia (Forssk) Chiov. Asian Journal of Plant Science and Research, 7(1), 9-15.
Sathish, S.S., Janakiraman, N. & Johnson, M. (2012). Phytochemical analysis of Vitex altissima L. Using UV-Vis, FTIR and GC-MS. Inter J of Pharma Sci and Drug Res. 4(1), 56-62.
Siva, G., Sivakumar, S., Kumar, G.P., Vigneswaran, M., Vinoth, S., Selavan, A.M. & Jayabalan, N. (2015). Optimization of elicitation with Jasmonic acid, characterization and antimicrobial activity of Psoralen from direct regenerated plants of Psoralea corylifolia L. Biocatalysis and Agricultural Biotechnology, 4(4), 624-631.
Sofowora, A., Ogunbodede, E. & Onayade, A. (2013). The role and place of medicinal plants in the strategies for disease prevention. African Journal of Traditional, Complementary and Alternative Medicines, 10(5), 210–229.
Sridharan, S., Meena, V., Kavitha, V. & Nayagam, A.A.J.(2011). GC-MS study and phytochemical profiling of Mimosa pudica L. J. Pharm. Res., 4, 741-742.
Tulika Tyagi & Mala Agarwal. (2017). GC-MS analysis of invasive aquatic weed, Pistia stratiotes L. and Eichhornia crassipes (mart.) solms. Int. J. Curr. Pharm. Res., 9(3), 111-117. DOI: https://doi.org/10.22159/ijcpr.2017.v9i 3.19 970
Vohra, A. & Kaur, H. (2011). Chemical investigation of medicinal plant Ajuga bracteosa. J. Nat. Prod. Plant Resour., 1(1), 37-45.
Zhang, X., Zhao, W., Wang, Y., Lu, j. & Chen, X. (2016). The chemical constituents and bioactivities of Psoralea corylifolia Linn. : A review. The American Journal of Chinese Medicine, 44(01), 35-60.
Section
Research Articles

How to Cite

Gas chromatography-Mass spectrometry analysis of bioactive compounds in chloroform extract of Psoralea corylifolia L. (2021). Journal of Applied and Natural Science, 13(4), 1225-1230. https://doi.org/10.31018/jans.v13i4.2884