Studies on the toxicity of 2-Methyltetrahydrofuran on the histopathology of gills of African catfish Clarias gariepinus
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Abstract
In the present study, investigation were carried out on gills of African cat fish Clarias gariepinus exposed to sub lethal concentrations (80mg/ml,400mg/ml and 800mg/ml) of 2-Methyltetrahydrofuran for 10 days. Lesions were observed in gills tissue of treated fish for long term exposure to Methyltetrahydrofuran (2MTHF). The occurrence and degree of alteration were positively related with the concentration of 2MTHF. Histological examination of the gills of fish treated with 80 mg/ml of 2MTHF for 10 days showed architectural loss, necrosis and desquamation of epithelial layer. Histological examination of the gills of fish treated with 400 mg/ml of 2MTHF for 10 days showed architectural loss, necrosis and mild vaccuolation. The gill filament exhibited telangiectesis, disorganisation of secondary gill lamellae and complete vaccuolation of gills treated with 800 mg/ml of 2MTHF for 10 days. The study indicated that 2MTHF had marked effects on the cyto-architecture of the gills of C. gariepinus. The degree of vaccuolation and necrosis were positively related with the concentration of 2MTHF.
Article Details
Article Details
Gill lamellae, 2-Methyltetrahydrofuran (2MTHF), Nacrosis, Telangiectesis, Vaccuolation
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